| Sabins | 1 |
| Sadler | 1 |
| Sakbuar | 1 |
| Salak | 1 |
| Sale | 1 |
| Salvadge | 2 |
| Salyer | 1 |
| Salyers | 4 |
| Sams | 2 |
| Samuelson | 2 |
| Sanchez | 2 |
| Sand | 1 |
| Sandercocks | 1 |
| Sanders | 23 |
| Sanderson | 2 |
| Sandidge | 1 |
| Sandifer | 1 |
| Sandon | 1 |
| Sandorf | 1 |
| Sandors | 1 |
| Sandy | 1 |
| Sanford | 1 |
| Sanford? | 1 |
| Sartor | 1 |
| Sasser | 2 |
| Satterfield | 1 |
| Sattler | 3 |
| Saucier | 2 |
| Saulmon | 1 |
| Saunders | 3 |
| Sauseda | 1 |
| Sawhill | 1 |
| Sawyer | 1 |
| Scales | 2 |
| Scanlon | 1 |
| Scattergood | 1 |
| Schaal | 1 |
| Schafer | 1 |
| Schatzel | 1 |
| Schaub | 19 |
| Schauwecker | 3 |
| Schermerhorn | 1 |
| Schettlee | 1 |
| Scheufler | 2 |
| Schiff | 3 |
| Schilling | 1 |
| Schindler | 4 |
| Schlamp | 6 |
| Schmidt | 2 |
| Schmith | 1 |
| Schmitz | 2 |
| Schneider | 9 |
| Schock | 3 |
| Schomaker | 1 |
| Schrieber | 1 |
| Schroeder | 1 |
| Schubert | 2 |
| Schultz | 6 |
| Schulz | 1 |
| Schumann | 1 |
| Schumpert | 1 |
| Schwanbeck | 1 |
| Schwarz | 1 |
| Schwemley | 1 |
| Schwerin | 1 |
| Scofield | 1 |
| Scoggin | 1 |
| Scoles | 1 |
| Scott | 40 |
| Scrivner | 1 |
| Scroggin | 1 |
| Scruggs | 3 |
| Scurlock | 1 |
| Seals | 1 |
| Searles | 1 |
| Sears | 5 |
| Seay | 1 |
| Sedberry | 24 |
| See | 1 |
| Seehale | 1 |
| Seibert | 2 |
| Self | 3 |
| Sellars | 4 |
| Sellers | 1 |
| Sellman | 1 |
| Sells | 1 |
| Selman | 1 |
| Senate | 1 |
| Sencenbaugh | 3 |
| Senn | 3 |
| Senter | 3 |
| Settle | 6 |
| Settles | 1 |
| Setzer | 1 |
| Severance | 1 |
| Sewell | 1 |
| Sexton | 2 |
| Seybold | 3 |
| Seymore | 1 |
| Shackleford | 1 |
| Shafer | 1 |
| Shafer or Scaggs | 1 |
| Shaner | 3 |
| Shanks | 1 |
| Shannon | 4 |
| Sharkey | 1 |
| Sharp | 10 |
| Sharpe | 4 |
| Shattuck | 1 |
| Shaw | 13 |
| Sheaffer | 2 |
| Shearin | 10 |
| Sheehan | 1 |
| Shehi | 1 |
| Shelby | 3 |
| Shellaberger | 1 |
| Shelton | 4 |
| Shepard | 6 |
| Shepherd | 7 |
| Sheridah | 1 |
| Sherlock | 9 |
| Sherrell | 1 |
| Sherrill | 2 |
| Sherrouse | 1 |
| Shields | 17 |
| Shifflett | 1 |
| Shiflet | 2 |
| Shilling | 1 |
| shimek | 1 |
| Shipp | 8 |
| Shippy | 1 |
| Shirey | 3 |
| Shirk | 1 |
| Shirkey | 1 |
| Shirley | 1 |
| Shisler | 1 |
| Shively | 2 |
| Shobe | 8 |
| Shockley | 1 |
| Shoemake | 7 |
| Shoemaker | 4 |
| Shofner | 2 |
| Sholar | 1 |
| Shores | 1 |
| Shorles | 1 |
| Short | 3 |
| Shoultz | 1 |
| Shrader | 1 |
| Shriver | 1 |
| Shufflin | 1 |
| Shull | 1 |
| Sibbell | 1 |
| Sibley | 1 |
| Sigler | 1 |
| Silver | 1 |
| Silvey | 1 |
| Simcock | 1 |
| Simcoe | 1 |
| Simmons | 1 |
| Simms | 7 |
| Simonds | 1 |
| Simons | 1 |
| Simpson | 6 |
| Simril | 3 |
| Sims | 8 |
| Sinclair | 1 |
| Sines | 1 |
| Singletary | 1 |
| Sinks | 1 |
| Sisco | 1 |
| Sisk | 1 |
| Sitton | 1 |
| Sixkiller | 1 |
| Sizemore | 5 |
| Skellenger | 1 |
| Skelton | 8 |
| Skiles | 1 |
| Skinner | 6 |
| Slack | 3 |
| Slade | 1 |
| Slagel | 1 |
| Slater | 1 |
| Sloan | 1 |
| Slobohm | 1 |
| Sloss | 1 |
| Slotwinski | 1 |
| Slusser | 1 |
| Small | 6 |
| Smalley | 1 |
| Smallwood | 10 |
| Smart | 3 |
| Smelcer | 1 |
| Smelly | 1 |
| Smiley | 2 |
| Smith | 184 |
| Smithers | 2 |
| Smithson | 7 |
| Smoke | 1 |
| Smokey | 2 |
| Smothers | 1 |
| Smyth | 24 |
| Snarr | 2 |
| Snavely | 1 |
| Snedeker | 2 |
| Snell | 1 |
| Snidow | 1 |
| Snively | 3 |
| Snodgrass | 1 |
| Snow | 5 |
| Snyder | 4 |
| Snyders | 8 |
| Sokolow | 1 |
| Sole | 5 |
| Solomon | 1 |
| Solt | 1 |
| Sonebarger | 2 |
| Sorenson | 1 |
| Sory | 1 |
| Soule | 2 |
| South | 2 |
| Southern | 1 |
| Souza | 1 |
| Sowell | 1 |
| Sparkman | 2 |
| Sparks | 3 |
| Speaks | 1 |
| Spears | 1 |
| Spence | 1 |
| Spencer | 6 |
| Sperry | 1 |
| SPICE | 1 |
| Spicer | 3 |
| Spillman | 1 |
| Spotswood | 1 |
| Spradlin | 1 |
| Spranders | 1 |
| Spriggs | 1 |
| Sprott | 2 |
| Sproul | 1 |
| Spurgin | 1 |
| Squire | 1 |
| St. Germain | 1 |
| St. John | 2 |
| Stacey | 1 |
| Stacy | 4 |
| Stadler | 1 |
| Stafford | 3 |
| Staggs | 1 |
| Stagner | 1 |
| Stahl | 1 |
| Stair | 1 |
| Stalford | 2 |
| Stallings | 1 |
| Stallworth | 18 |
| Stambaugh | 2 |
| Stamm | 1 |
| Stanbock | 12 |
| Stanford | 2 |
| Stangel | 1 |
| Stanhope | 13 |
| Stanley | 16 |
| Stanton | 1 |
| Staples | 2 |
| Stapleton | 3 |
| Stark | 2 |
| Starling | 2 |
| Starr | 5 |
| Statler | 1 |
| Staton | 1 |
| Stauber | 1 |
| Steadman | 2 |
| Stearns | 1 |
| Stebbins | 1 |
| Steed | 1 |
| Steele | 19 |
| Steen | 1 |
| Steere | 3 |
| Stefan | 1 |
| Stegall | 1 |
| Stein | 2 |
| Stengel | 1 |
| Stephens | 4 |
| Stephenson | 1 |
| Sterrett | 2 |
| Stevens | 8 |
| Stevenson | 17 |
| Steward | 2 |
| Stewart | 42 |
| Stice | 4 |
| Stiffy | 1 |
| Stiger | 1 |
| Stiley | 1 |
| Stinson | 8 |
| Stith | 1 |
| Stock | 1 |
| Stocker | 1 |
| Stoddert | 3 |
| Stokes | 3 |
| Stokesbury | 1 |
| Stollworth | 1 |
| Stom | 1 |
| Stone | 21 |
| Stoner | 1 |
| Story | 5 |
| Stout | 19 |
| Stover | 1 |
| Stow | 8 |
| Strain | 5 |
| Strange | 5 |
| Stratman | 1 |
| Straton | 1 |
| Strayer | 2 |
| Strechl | 1 |
| Strickland | 6 |
| Stringer | 2 |
| Stringfellow | 10 |
| Striplin | 50 |
| Stripling | 27 |
| Strode | 1 |
| Strohmeyer | 1 |
| Strong | 1 |
| Strother | 1 |
| Struckmeyer | 1 |
| Struggle | 1 |
| Stuart | 3 |
| Stubblefield | 3 |
| Studdard | 1 |
| Stufflebeam | 1 |
| Stum | 1 |
| Sturges | 2 |
| Stutz | 3 |
| Stutzman | 2 |
| Sublette | 1 |
| Sudduth | 1 |
| Suitts | 1 |
| Sullivan | 4 |
| Summers | 4 |
| Sumner | 1 |
| Susan | 1 |
| Sutherland | 1 |
| Sutphen | 1 |
| Suttle | 7 |
| Sutton | 7 |
| Swafford | 2 |
| Swain | 1 |
| Swallows | 1 |
| Swann | 2 |
| Swanson | 1 |
| Swartz | 3 |
| Sweaingen | 3 |
| Swealt | 1 |
| Swearingen | 1 |
| Sweazy | 1 |
| Sweet | 5 |
| Swetzoff | 1 |
| Swick | 1 |
| Swift | 2 |
| Swink | 1 |
| Sylvina | 1 |
| Symmes | 1 |
updated - GMB 06/16/07